Recognition of Cd1d-Sulfatide Mediated by A Type Ii Natural Killer T Cell Antigen Receptor

Onisha Patel,Daniel G Pellicci,Stephanie Gras,Maria L Sandoval-Romero,Adam P Uldrich,Thierry Mallevaey,Andrew J Clarke,Jérôme Le Nours,Alex Theodossis,Susanna L Cardell,Laurent Gapin,Dale I Godfrey,Jamie Rossjohn

Nature immunology（2012）

引用 121|浏览7

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摘要

Natural killer T cells (NKT cells) recognize lipid antigens presented by CD1d. Zajonc and Rossjohn and their colleagues describe molecular interactions between type II NKT cell antigen receptors and CD1d-ligand complexes, which demonstrate distinct modes of recognition used by the receptors.

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关键词

NKT cells,Structural biology,Biomedicine,general,Immunology,Infectious Diseases

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