Endothelin system polymorphisms in tilt test-induced vasovagal syncope.

Sandro Sorrentino,Cinzia Forleo,Massimo Iacoviello,Pietro Guida,Valentina D'Andria,Stefano Favale

Clinical autonomic research : official journal of the Clinical Autonomic Research Society（2009）

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摘要

In conclusion, the 3A/4A polymorphism of the EDN1 gene affects susceptibility to syncope, and the 4A variant associated with increased endothhelin-1 expression may promote vasodepressive hemodynamic responses during tilt testing.

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