Ubiquitin chain conformation regulates recognition and activity of interacting proteins

Yu Ye,Georg Blaser,Mathew H. Horrocks,Maria J. Ruedas-Rama,Shehu Ibrahim, Alexander A. Zhukov,Angel Orte,David Klenerman,Sophie E. Jackson,David Komander

NATURE（2012）

引用 204|浏览2

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摘要

Single-molecule FRET assays used to probe the conformational dynamics of ubiquitin chains reveal that conformational selection is an important mechanism of ubiquitin chain recognition.

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Biophysical chemistry

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