[Construction of bicistronic eukaryotic vector containing basic fibroblast growth factor and study of their functions in gene therapy for hearing impairment].

Li Shi,Ming-min Dong,Wen-jie Shi,Yin-yan Hu,Wei Guo,Suo-qiang Zhai,Wei-yan Yang

Zhonghua er bi yan hou ke za zhi（2003）

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摘要

bFGF/EGFP fusion protein not only expressed in hair cells of guinea pig but also showed significant bFGF activity and autonomous fluorescence. IRES induced exogenous gene could enter the hair cells.

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关键词

bicistronic eukaryotic vector,basic fibroblast growth factor,gene therapy,hearing

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