A rapid liquid chromatography tandem mass spectrometry-based method for measuring propranolol on dried blood spots

Maria Luisa Della Bona,Sabrina Malvagia,Fabio Villanelli,Elisa Giocaliere,Daniela Ombrone,Silvia Funghini,Luca Filippi,Giacomo Cavallaro,Paola Bagnoli,Renzo Guerrini,Giancarlo la Marca

Journal of Pharmaceutical and Biomedical Analysis（2013）

引用 27|浏览16

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摘要

Propranolol, a non-selective beta blocker drug, is used in young infants and newborns for treating several heart diseases; its pharmacokinetics has been extensively evaluated in adult patients using extrapolation to treat pediatric population.

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关键词

DBS,LC–MS/MS,MRM,ROP,β-ARs,HPLC,MS,GC/MS,LLOD,LLOQ,Hct

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