Identifying Ki-67 specific miRNA-mRNA interactions in malignant astrocytomas.

Yanwei Liu,Kai Tang,Wei Yan,Yongzhi Wang,Gan You,Chunsheng Kang,Tao Jiang,Wei Zhang

Neuroscience Letters（2013）

引用 18|浏览24

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摘要

•Identified Ki-67 specific miRNA–mRNA interactions in malignant astrocytomas.•MiR-218 inhibits cellular proliferation by down-regulating Ki-67 specific mRNAs.•High expression levels of Ki-67 protein suggest a short survival time for patients with AA.

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关键词

Anaplastic astrocytoma,Glioblastoma multiforme,Ki-67,miRNA,mRNA

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