Reconfiguration of the proteasome during chaperone-mediated assembly

Soyeon Park,Xueming Li,Ho Min Kim,Chingakham Ranjit Singh,Geng Tian,Martin A. Hoyt,Scott Lovell,Kevin P. Battaile,Michal Zolkiewski,Philip Coffino,Jeroen Roelofs,Yifan Cheng,Daniel Finley

NATURE（2013）

引用 75|浏览21

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摘要

The proteasome degrades ubiquitin-conjugated substrates; here, structural and functional insights from studies in yeast reveal that it is reconfigured during chaperone-mediated assembly.

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关键词

Biochemistry, Electron microscopy

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