Emergency Life Support System Aiming Preprimed Oxygenator.

Takashi Isoyama,Koki Ariyoshi,Kyosuke Nii,Itsuro Saito,Kazuyoshi Fukunaga,Yusuke Inoue,Toshiya Ono,Kohei Ishii,Shintaro Hara,Kou Imachi,Madoka Takai,Yusuke Abe

2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)（2013）

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摘要

Development have been achieved of a new blood pump for next generation Percutaneous Cardio-Pulmonary Support (PCPS) system and a novel surface coating method for silicone membrane hollow fiber by physical adsorption using a copolymer composed of a 2-Methacryloyloxyethyl phosphorylcholine (MPC) unit and a hydrophobic unit. The new blood pump, named the Troidal Convolution Pump (TCP), is based on the principle of a cascade pump and perfused 5 L/min and 350 mmHg at 2450 rpm. The novel copolymer composed of 30% MPC unit and 3-(methacryloyloxy) propyltris (trimethylsiloxy) silane (MPTSSi) unit (PMMSi30) was the most suitable molecular design on a silicone surface. The PMMSi30 coated surface adsorbed 7.2 % as much protein a non-coated surface adsorbed.

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关键词

biomedical equipment,biomedical materials,blood,coatings,membranes,patient treatment,polymer blends,polymer films,pumps,2-methacryloyloxyethyl phosphorylcholine,3-(methacryloyloxy)propyltris(trimethylsiloxy)silane,MPC unit,MPTSSi unit,PMMSi30,TCP,Troidal Convolution Pump,blood pump,cascade pump principle,copolymer,emergency life support system,hydrophobic unit,next generation PCPS system,percutaneous cardiopulmonary support system,physical adsorption,preprimed oxygenator,pressure 350 mm Hg,silicone membrane hollow fiber,surface coating method

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