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Hepatitis C Virus‐specific Cellular Immune Responses in Sustained Virological Responders with Viral Persistence in Peripheral Blood Mononuclear Cells

Liver international(2013)

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摘要
Hepatitis C virus (HCV)‐RNA detection in peripheral blood mononuclear cells (PBMCs) after recovery from HCV infection, is a type of occult HCV infection although is unclear how the viral persistence in PBMCs affects HCV‐specific T‐cell responses. The aim of this study was to investigate if cellular immune responses are modified by HCV persistence in PBMCs.
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关键词
flow cytometry,occult HCV infection,peripheral blood mononuclear cells,real-time PCR,sustained virological responders,T-cell response
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