Antithymic factor in schizophrenia patients]

The paper concerns results of the studies, accomplished according to the WHO project within the framework of international collaboration in biological psychiatry. It was demonstrated that the blood sera of mental patients and normals possess antithymic activity. However there are statistically significant differences between the groups of patients and normals with regard to the level of sera antithymic activity (0,22 +/- 0,05 in normals and 0,47 +/- 0,04 in patients, p < 0,05). The medium level of antithymic activity in the group of schizophrenic patients depends upon the duration of the disease. The level of sera antithymic activity was significantly higher (p < 0,05) in the group of patients with a duration of the disease less than 5 years and lower in patients with a duration of the process over 5 years.