Reconstruction of functional endometrium-like tissue in vitro and in vivo using cell sheet engineering.

Soichi Takagi,Tatsuya Shimizu,Goro Kuramoto,Ken Ishitani,Hideo Matsui,Masayuki Yamato,Teruo Okano

Biochemical and Biophysical Research Communications（2014）

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摘要

•Endometrial cell sheets reconstructed endometrium-like tissues in vitro and in vivo.•Endometrium-like tissues retained a function of hormonal receptors.•Endometrium-like tissues in vivo formed uterus-specific glandular structures.•Endometrium-like tissues in vivo formed functional secretory glands.

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关键词

Regeneration,Endometrium,Glandular structure,Hormonal receptors,Cell sheet

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