Development of a Dynamic Multiple Reaction Monitoring Method for Determination of Digoxin and Six Active Components of Ginkgo Biloba Leaf Extract in Rat Plasma.

•This is the first report on the determination of DGX and six main components of GBE in rat plasma.•This study developed an effective DMRM method, the sensitivity and reproducibility is much higher than MRM.•This study showed the existence of herbal–drug interaction in GBE and DGX.