Tailoring the GVHD prophylaxis regimen according to transplantation associated toxicities-Substituting the 3rd dose of methotrexate to mycophenolate mofetil.

Ron Ram,Corina Herscovici,Dikla Dahan,Moshe Israeli,Juliet Dreyer,Anat Peck,Ofer Shpilberg,Moshe Yeshurun

Leukemia Research（2014）

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摘要

•Patients with post-transplant toxicities given MMF had a higher incidence of grade 2–4 acute GVHD.•Patients with post-transplant toxicities given MMF had similar incidence of grade 3-4 acute GVHD.•Incidences of chronic GVHD, relapse rate, NRM and OS were similar in both group.

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关键词

GVHD,Hematopoietic cell transplantation,Methotrexate,MMF

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