Cold hypersensitivity increases with age in mice with sickle cell disease.

PAIN®(2014)

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摘要
Sensory neurons from sickle cell disease mice are sensitized to cold, mirroring behavioral observations, and have increased expression of endothelin 1 and tachykinin receptor 1.
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关键词
TRPA1,TRPM8,Endothelin 1,C fiber,Aging,KCNK
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