Stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid.

JOURNAL OF ORGANIC CHEMISTRY(2014)

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摘要
A rhodium-catalyzed cyclopropanation of 1-fluoro-1-(phenylsulfonyl)-ethylene and diazo esters is described as an effective method for the stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid. This process provides an example of the cyclopropanation of electron-deficient olefin and diazoacetates.
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