An unconventional BST-2 function: down-regulation of transient protein expression.

Jaraspim Narkpuk,Asawin Wanitchang,Jarin Kramyu,Phanramphoei Namprachan Frantz,Anan Jongkaewwattana,Samaporn Teeravechyan

Biochemical and Biophysical Research Communications（2014）

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摘要

•BST-2 overexpression negatively affects influenza virus reverse genetics.•BST-2 decreases transient protein expression.•N- and C-termini of BST-2 play roles in affecting protein expression.•Protein down-regulation may serve as a route for viral inhibition by BST-2.

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