Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia.

Neuroscience（2014）

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摘要

•Post-training administration of morphine impairs memory retrieval.•Pre-test administration of nicotine reversed morphine-induced amnesia.•Intra-CeA injection of MDMA potentiated nicotine response.•Intra-CeA injection of mecamylamine inhibited potentiative effect of MDMA.•Blockade of the CeA 5-HT1A receptors inhibited potentiative effect of MDMA.

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关键词

5-HT1A,ANOVA,CeA,CPP,MDMA,MORs,nACh,nAChRs

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