A novel evaluation method of survival motor neuron protein as a biomarker of spinal muscular atrophy by imaging flow cytometry.

Biochemical and Biophysical Research Communications(2014)

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摘要
•We report a novel evaluation method of SMN protein by imaging flow cytometry.•Imaging flow cytometry could evaluate the cellular localization of SMN protein.•Imaging flow cytometry could evaluate the effects on VPA-treated SMA fibroblasts.
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关键词
Spinal muscular atrophy,Survival motor protein,Biomarker,Imaging flow cytometry,Valproic acid
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