Use of lidocaine in endotracheal intubation. Blood and urine concentrations in patients and deceased after unsuccessful resuscitation

Cora Wunder,Jens Meier,Christian Reyher,Verena Könitz,Alexander Paulke,Kai Zacharowski,Stefan W. Toennes

Forensic Science International（2014）

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摘要

•From an endotracheal tube coated with lidocaine it is absorbed.•Lidocaine/MEGX concentrations were determined in blood/urine in ventilated patients.•Lidocaine/MEGX concentrations are in the same range as postmortem concentrations.•Lidocaine/MEGX concentrations <1/<0.05mg/l indicate resuscitation prior to death.

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关键词

Forensic toxicology,Lidocaine,Local anesthetics,Postmortem toxicological analysis,Cardiac surgery,Resuscitation

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