Lung pathogenicity of European genotype 3 strain porcine reproductive and respiratory syndrome virus (PRRSV) differs from that of subtype 1 strains.

Eefke Weesendorp,Johanna M J Rebel,Ditta J Popma-De Graaf,Helmi P D Fijten,Norbert Stockhofe-Zurwieden

Veterinary Microbiology（2014）

引用 43|浏览8

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摘要

•We studied pathological responses after infection with EU PRRSV subtype 3 or 1.•EU subtype 3 PRRSV is more pneumovirulent that subtype 1.•EU subtype 3 induced a stronger early inflammatory response than subtype 1.•EU subtype 3 was cleared faster from tissues than subtype 1.

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关键词

Porcine reproductive and respiratory syndrome virus,Pathogenesis,Immune response,Genetic subtypes

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