Using SomaticSniper to Detect Somatic Single Nucleotide Variants.

David E Larson,Travis E Abbott,Richard K Wilson

Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]（2014）

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摘要

Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next generation sequencing data. This protocol describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software.

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关键词

next-generation sequencing,somatic variant calling,somaticsniper,next generation sequencing

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