Highly sensitive and selective detection of miRNA: DNase I-assisted target recycling using DNA probes protected by polydopamine nanospheres.

Yi Xie,Xiaoyan Lin,Yishun Huang, Rujun Pan,Zhi Zhu,Leiji Zhou,Chaoyong James Yang

Chemical communications (Cambridge, England)（2015）

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摘要

Based on the protective properties of polydopamine nanospheres for DNA probes against nuclease digestion, we have developed a DNase I-assisted target recycling signal amplification method for highly sensitive and selective detection of miRNA.

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