Nanoparticle-based technologies for retinal gene therapy.

•Monogenic retinal diseases are great targets for genetic therapies.•Viral and non-viral (nanoparticle) approaches have been tested.•Various types of nanoparticles have been tested successfully in the eye.•The retinal pigment epithelium is the easiest retinal cell type to transfect.•Some nanoparticles such as CK30-PEG also transfect photoreceptors.