Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

Matthias Merker, Camille Blin,Stefano Mona,Nicolas Duforet-Frebourg,Sophie Lecher,Eve Willery,Michael G B Blum,Sabine Rüsch-Gerdes,Igor Mokrousov,Eman Aleksic,Caroline Allix-Béguec, Annick Antierens,Ewa Augustynowicz-Kopeć,Marie Ballif,Francesca Barletta,Hans Peter Beck,Clifton E Barry III,Maryline Bonnet,Emanuele Borroni,Isolina Campos-Herrero,Daniela Cirillo,Helen Cox,Suzanne Crowe,Valeriu Crudu,Roland Diel,Francis Drobniewski,Maryse Fauville-Dufaux,Sébastien Gagneux,Solomon Ghebremichael,Madeleine Hanekom,Sven Hoffner,Wei-wei Jiao,Stobdan Kalon,Thomas A Kohl,Irina Kontsevaya,Troels Lillebæk,Shinji Maeda,Vladyslav Nikolayevskyy,Michael Rasmussen,Nalin Rastogi,Sofia Samper,Elisabeth Sanchez-Padilla,Branislava Savic,Isdore Chola Shamputa,Adong Shen,Li-Hwei Sng,Petras Stakenas,Kadri Toit,Francis Varaine,Dragana Vukovic,Céline Wahl,Robin Warren,Philip Supply,Stefan Niemann,Thierry Wirth

Nature Genetics（2015）

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摘要

Thierry Wirth, Philip Supply, Stefan Niemann and colleagues analyze 4,987 Mycobacterium tuberculosis strains of the Beijing lineage isolated from 99 countries. They report whole-genome sequencing of 110 representative strains, characterize global population structure and reconstruct the evolutionary history of this lineage.

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关键词

Bacteriology,Tuberculosis,Biomedicine,general,Human Genetics,Cancer Research,Agriculture,Gene Function,Animal Genetics and Genomics

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