Neuroprotective effects of crocin against traumatic brain injury in mice: Involvement of notch signaling pathway.

Kai Wang,Lei Zhang,Wei Rao,Ning Su,Hao Hui,Li Wang,Cheng Peng,Yue Tu,Sai Zhang,Zhou Fei

Neuroscience Letters（2015）

引用 73|浏览41

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摘要

•Pretreatment of crocin (20mg/kg) conferred neuroprotective effects on the mice against TBI.•Pretreatment of crocin (20mg/kg) significantly increased the Notch signaling activation after TBI.•Inhibition of Notch signaling attenuated the ability of crocin to protect mice against TBI.

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关键词

Traumatic brain injury,Crocin,Notch

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