Human DNA polymerase θ grasps the primer terminus to mediate DNA repair
NATURE STRUCTURAL & MOLECULAR BIOLOGY(2015)
摘要
DNA polymerase θ is involved in alternative end-joining repair of DNA double-strand breaks. Structural and biochemical analyses shed light on pol θ's ability to prime DNA synthesis from nonoptimal base-pairing.
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关键词
nature structural and molecular biology, science
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