Molecular diversity of Bacillus anthracis in the Netherlands: Investigating the relationship to the worldwide population using whole-genome SNP discovery

Infection, Genetics and Evolution(2015)

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摘要
•CanSNP typing of isolates from Dutch anthrax outbreaks was performed.•The phylogenetic diversity is analogous to findings in other European countries.•Phylogenetic relationships with strains from other parts of the world is discussed.•New HRM assays based on diagnostic SNPs were developed for epidemiological purposes.
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关键词
Bacillus anthracis,Whole genome sequencing,Single nucleotide polymorphism,Molecular typing,Comparative genomics,High resolution melting (HRM)
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