Heat shock at higher cell densities improves measles hemagglutinin translocation and human GRP78/BiP secretion in Saccharomyces cerevisiae.

Rūta Zinkevičiūtė,Edita Bakūnaitė,Evaldas Čiplys,Raimundas Ražanskas,Jurgita Raškevičiūtė,Rimantas Slibinskas

New Biotechnology（2015）

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摘要

•Heat shock improves measles hemagglutinin translocation into the ER of yeast cells.•Elevated temperature also increased secretion of recombinant human GRP78/BiP in yeast.•Heat shock improved endogenous invertase yield by approximately 2.7-fold.•Heat shock should be applied at higher cell densities of yeast culture.

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