Investigating the dynamics of recombinant protein secretion from a microalgal host.

Kyle J Lauersen,Isabel Huber,Julian Wichmann,Thomas Baier,Andreas Leiter,Volker Gaukel,Viktor Kartushin,Anke Rattenholl,Christian Steinweg,Lena von Riesen,Clemens Posten,Frank Gudermann,Dirk Lütkemeyer,Jan H Mussgnug,Olaf Kruse

Journal of Biotechnology（2015）

引用 36|浏览13

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摘要

•Algal cultivation parameters significantly affect secreted recombinant protein titres.•Chlamydomonas cultivation in cGMP grade wave-bag systems is possible.•Flat-panel bioreactors generate equivalent biomass as small-scale batch cultures.

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