Production of IL-10 by CD4 + regulatory T cells during the resolution of infection promotes the maturation of memory CD8 + T cells

Brian J Laidlaw,Weiguo Cui,Robert A Amezquita,Simon M Gray,Tianxia Guan,Yisi Lu,Yasushi Kobayashi,Richard A Flavell,Steven H Kleinstein,Joe Craft,Susan M Kaech

NATURE IMMUNOLOGY（2015）

引用 186|浏览12

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摘要

The precise factors that control effective memory formation by T cells are unclear. Kaech et al . demonstrate that regulatory T cell–produced IL-10 is critical for the generation of CD8 + memory cells.

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nature immunology, science

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