Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Nature genetics(2015)
摘要
Rinse Weersma, Carl Anderson and colleagues report the results of a trans-ancestry association study of inflammatory bowel disease. They implicate 38 new susceptibility loci, and show that the variance explained by each IBD risk locus is consistent across diverse ancestries, with a few notable exceptions.
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关键词
Crohn's disease, Ulcerative colitis, Genome-wide association studies
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