Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells

Jun Liu, Chongxi Fan,Liming Yu,Yang Yang,Shuai Jiang, Zhiqiang Ma, Wei Hu,Tian Li,Zhi Yang, Tian Tian,Weixun Duan,Shiqiang Yu

Cytokine（2016）

引用 35|浏览44

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摘要

•Pterostilbene can effectively attenuates vascular endothelial inflammatory response.•This effect is at least partially dependent on the attenuation of endoplasmic reticulum stress (ERS).•The inhibition of the ERS provides protection against endothelial inflammatory reactions.

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ATF6,BSA,CCK8,CHOP,DMSO,eIF2α,ERAD,ER,ERS,FBS,GRP78,HUVECs,ICAM1,IL-8,IRE1,LSD,MCP-1,MMP9,OD,PBS,p-eIF2α,PERK,PT,SD,sICAM1,siRNA,TBST,THA,TNF-α,UPR

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