Expression pattern of the Hedgehog signaling pathway in pituitary adenomas.

Maria P Yavropoulou,Anna Maladaki,Konstantina Topouridou,Vasiliki Kotoula,Chris Poulios,Emily Daskalaki,Nikolaos Foroglou,George Karkavelas,John G Yovos

Neuroscience Letters（2016）

引用 10|浏览15

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摘要

•Hedgehog signaling pathway is downregulated in non-functioning pituitary adenomas.•Somatotropinomas display an overexpression of Hedgehog related genes.•Expression of Notch 3 and Jagged-1 is down-regulated in somatotropinomas.

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关键词

Notch signaling,Hedgehog signaling,Non-functioning pituitary adenomas,Somatotropinomas

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