A Case of Plasmacytoid Variant of Bladder Cancer with a Single Penile Metastasis and a Complete Response to Carboplatin-Based Chemotherapy and Review of the Literature.

Bladder cancer is the most common tumor of the urinary system and the ninth most common malignancy worldwide. It has been estimated that 386,000 new cases are diagnosed annually, resulting in 150,000 deaths worldwide.1 Urothelial carcinoma (UC) is the predominant histologic type in Western Europe and the United States, where it accounts for approximately 90% of all bladder cancer cases.2 UC with plasmacytoid morphology, first described in 1991 as “similar to plasma cells seen in myeloma,” is a rare variant of UC and has been included in the World Health Organization classification since 2004.