A Community Based Primary Prevention Programme for Type 2 Diabetes Integrating Identification and Lifestyle Intervention for Prevention: the Let's Prevent Diabetes Cluster Randomised Controlled Trial.

Preventive Medicine(2016)

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摘要
•To date there has been a dearth of evidence for T2DM prevention in a UK community setting.•This is the first large scale RCT to evaluate the effect of a T2DM prevention intervention (Let's Prevent) in a UK community setting.•This study showed a non-significant 25%–35% reduction in the progression to T2DM at 3years with a number of improvements in secondary outcomes and health behaviours.•Let's Prevent provides a model of T2DM prevention that can be directly implemented and commissioned within primary care or public health services using existing infrastructure for the delivery of structured education.•Future research should focus on increasing uptake to screening and attendance at education sessions.
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关键词
Type 2 diabetes,Pre-diabetes,Prevention,Lifestyle,Clinical trial
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