Cassane diterpenes from the seed kernels of Caesalpinia sappan

Phytochemistry(2016)

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摘要
•Chemical constituents of the seed kernel of Caesalpinia sappan were investigated.•Eight cassane diterpenes named tomocins A–H were isolated and structurally characterized.•Tomocins showed anti-austerity activity against PANC-1 human pancreatic cancer cells.•Potential use of tomocins as lead structures for anti-austerity drug development.
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关键词
Caesalpinia sappan,Caesalpiniaceae,Cassane diterpene,Antiausterity agent,PANC-1
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