Cassane diterpenes from the seed kernels of Caesalpinia sappan
Phytochemistry(2016)
摘要
•Chemical constituents of the seed kernel of Caesalpinia sappan were investigated.•Eight cassane diterpenes named tomocins A–H were isolated and structurally characterized.•Tomocins showed anti-austerity activity against PANC-1 human pancreatic cancer cells.•Potential use of tomocins as lead structures for anti-austerity drug development.
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关键词
Caesalpinia sappan,Caesalpiniaceae,Cassane diterpene,Antiausterity agent,PANC-1
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