Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Denise Martinez-Zapien,Francesc Xavier Ruiz,Juline Poirson,André Mitschler,Juan Ramirez,Anne Forster,Alexandra Cousido-Siah,Murielle Masson,Scott Vande Pol,Alberto Podjarny,Gilles Travé,Katia Zanier

NATURE（2016）

引用 425|浏览17

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摘要

WebStructural details of how oncogenic human papilloma viruses induce cancer by targeting the tumour suppressor p53 for ubiquitin-mediated degradation.

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关键词

Tumour suppressors,X-ray crystallography,Tumour virus infections

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