Development of a mushroom powder Certified Reference Material for calcium, arsenic, cadmium and lead measurements.

Isotope dilution mass spectrometry and standard addition techniques were developed for the analysis of four elements (Ca, As, Cd and Pb) in a mushroom powder material. Results from the validated methods were compared to those of other national metrology institutes in the CCQM-K89 intercomparisons and the results were in excellent agreement with the reference values. The same methods were then used for the assignment of reference values to a mushroom powder Certified Reference Material (CRM). The certified values obtained for Ca, As, Cd and Pb were 1.444 +/- 0.099 mg/g, 5.61 +/- 0.59 mg/kg, 1.191 +/- 0.079 mg/kg and 5.23 +/- 0.94 mg/kg, respectively. The expanded measurement uncertainties were obtained by combining the uncertainty contributions from characterization (u(char)) and between-bottle homogeneity (u(bb)). (C) 2015 Elsevier Ltd. All rights reserved.