Novel mutation 928G>C ofMEN1gene in a familial multiple endocrine neoplasia type 1 case (MEN1) with co-existence of insulinoma and glucagonoma1名同时合并胰岛素瘤与胰高血糖素瘤的家族性多发性内分泌腺瘤1型（MEN1）患者的MEN1基因出现了新的928G>C突变

(CT) scan revealed a tumor mass (1.2 × 0.7 cm) in the tail of the pancreas. Pituitary magnetic resonance imaging (MRI) scan showed a nodule in the lower left of pituitary and MIBI scan of parathyroid gland found abnormal uptake of MIBI in the right thyroid lobe, suggestive of parathyroid adenoma. A diagnosis of familial MEN1 presenting with insulinoma, hyperparathyroidism and prolactin-secreting pituitary adenoma was made based on her clinical data and family history. The patient underwent laparoscopic resection of pancreatic tail with preservation of the spleen. A tumor (4 × 3 cm) was found in the pancreatic tail. The tumor was close to the splenic hilum and located between the two splenic arteries. Post