TOPICAL MITOMYCIN C IN THE ENDOSCOPIC MANAGEMENT OF LARYNGOTRACHEAL STENOSIS

PURPOSE: Topical applications of Mitomycin-C (MMC) following endoscopic dilation of laryngotracheal stenosis delays scarring/re-stenosis of the airways but long-term relapses are common. The effects of repeated MMC applications have not been studied. This study evaluates the hypothesis that two applications of MMC will decrease the rate of re-stenosis when compared to a single application.