Pre-and postoperative cerebral blood flow changes in patients with idiopathic normal pressure hydrocephalus measured by computed tomography (CT)-perfusion

Computed tomography perfusion (CTP) is an established technique, but has not yet been applied to idiopathic normal pressure hydrocephalus (iNPH), in which cerebral blood flow (CBF) is of pathophysiological, diagnostic and prognostic interest. The aim of this work was to determine the pre-and postoperative regional and global CBF in iNPH by CTP, expecting the results to confirm the findings of a perfusion evaluation on the same group of patients and controls, previously performed with magnetic resonance perfusion (MRP).