Pulmonary Artery Proportional Pulse Pressure Predicts Adverse Clinical Outcomes in Group 1 Pulmonary Hypertension (analysis of the NIH Pulmonary Hypertension Registry)

The National Institute of Health (NIH) registry for primary pulmonary hypertension (PPH) established prognostic factors for PPH (now WHO group 1 PH). The “NIH risk stratification equation” includes: mean right atrial pressure, mean pulmonary artery pressure (mPAP), and cardiac index.We recently showed that a low pulmonary artery (PA) proportional pulse pressure (PAPP, range 0-1, defined as [PA systolic pressure - PA diastolic pressure]/PA systolic pressure) is independently associated with poor prognosis in chronic heart failure.