Topoisomerase poisoning by genistein in the intestine of rats

Simone Baechler,Sebastian T Soukup,Almut F Molzberger,Sabine E Kulling,Patrick Diel,Doris Marko

Toxicology Letters（2016）

引用 10|浏览8

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摘要

•Genistein (s.c.) significantly increases the amount of covalent topoisomerase IIα and β-DNA complexes in the gut.•More persistent effects on covalent topoisomerase IIα and β-DNA complexes in the colon compared to the duodenum.

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关键词

BW,CTRL,GEN,ICE-bioassay,IDD,IRD,PND

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