Microbial transformations of betulinic and betulonic acids

Animesh Goswami,Zhiwei Guo, Thomas P. Tully, Frank A. Rinaldi,Xiaohua Stella Huang,Jacob J. Swidorski,Alicia Regueiro-Ren

Journal of Molecular Catalysis B: Enzymatic（2015）

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摘要

•Enzymatic oxidations of betulinic and betulonic acids.•Biotransformations with two bacteria and two fungi were studied.•Several di-, tri-, tetrahydroxy and multiply oxidized compounds were obtained.•Five novel compounds were produced and characterized.

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关键词

Betulinic acid,Betulonic acid,Microbial transformation,Enzymatic hydroxylation,Enzymatic oxidation

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