Targeting cathepsins-tBid-mitochondial apoptotic signaling pathway in astrocytes contributes to neuroprotection against cerebral ischemia (LB627)

Huiling Zhang,Min Xu,Lei Yang,Jiaguo Rong,Yong Ni,Kazumi Ishidoh,Nobuhiko Katunuma

The FASEB Journal（2014）

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ABSTRACT The roles of cathepsins in the ischemic astrocytic injury remain unclear. Here we test the hypothesis that activation of cathepsin B and L contributes to the ischemic astrocyte injury via ...

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