Snp Selection For Psychiatric Disease Association Based On Allele Frequency Plots

DATA QUALITY AND HIGH-DIMENSIONAL DATA ANALYSIS(2009)

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摘要
Last years the study of the influence of genetic factors in the susceptibility to some common diseases has been obtaining satisfactory results. These results contribute to the prevention of these diseases as well as to design personalized treatments. The present work introduces a technique based on 2D representations of the genetic data that can contribute to find these disease associations. A real case application is presented in which we analyze the relation between the allele pair values of 748 Single Nucleotide Polymorphisms (SNPs) and the susceptibility to seven common psychiatrical disorders.
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关键词
SNP, Allele Frequency Plots
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