On the Functional Approach to Locally D-Optimum Design for Multiresponse Models

Viatcheslav B Melas,Lyudmila A Krylova,Dariusz Ucinski

mag（2013）

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摘要

D-optimum experimental designs are investigated for a multiresponse kinetic model of two consecutive first-order reactions. The model is nonlinear and consists of a set of ordinary differential equations. We demonstrate how the functional approach can be adapted to numerically construct optimal designs in this setting.

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关键词

Functional Approach, Multiresponse Model, Consecutive First-order Reactions, Support Points, Single Response Model

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