Multiple Osteochondromata after Total Body Irradiation: A Case Report.

We present a rare case of multiple osteochondromata after total body irradiation in a bone marrow recipient. The patient was a 9-year-old boy. He had been given 13.2 Gy of total body irradiation (TBI) before allogeneic bone marrow transplantation (BMT) at the age of one because of acute lymphoblastic leukemia (ALL). He did not have a family history of hereditary multiple osteochondromatosis. Osteochondromata presented at the left clavicle, bilateral scapulae, right distal femur, and right proximal tibia. The lesions of the left clavicle and bilateral scapulae were excised. Histological features of resected specimens were those of osteochondroma, showing no evidence of malignant transformation.Although radiation is recognized to be a cause of osteochondroma, reports of TBI are rare. TBI should be considered as one of the causes of multiple osteochondromata.