The scale up of chemical reactions

Nature Reviews Methods Primers(2022)

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摘要
The scaling up of a chemical reaction is a complex process. Chemists should pay special attention to a number of key factors, including the choice of route, reagents and solvents; health and safety considerations; the isolation and purification of the desired product; and the development of robust supporting analytical methodology.
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关键词
mixing,stirred tank reactor,heat transfer
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