PP049-MON: Sarcopenia, Anthropometry and Malnutrition in Relation to 2-Y Mortality in Geriatric Patients

Rationale: Over 400,000 people are supported by tube feeding in Japan. Excess protein raise BUN and lead to renal failure. Lack of protein lower albumin concentration and lead to dysfunction. But optimal protein concentration is disputable. Methods: We changed protein concentration at one time from 1.25 g/kg body weight to 1.00 g/kg body weight without calorie change (25 kcal/kg body weight). And measured body weight, albumin, BUN, Cr, e-GFR before change, 1, 2, 6, 12 months after change. At first sixty two patients. One year after, forty one individuals were in hospital (m:f 19:22, age 80.9±10.8). We evaluated these patients’ data. Results: Body weight 40.9±7.7, 41.0±7.8, 41.2±8.1, 41.2 ±8.1, 41.3±8.6, no change. Alb 3.06±0.33, 3.02±0.34, 3.07±0.37, 3.05±0.35, 2.89±0.37, decrease in 12 months after. BUN 23.2±10.3, 17.6±7.3, 17.2±5.7, 17.5±7.1, 19.2±11.1, decrease in 1 month after. Cr 0.630±0.33, 0.615±0.3, 0.586±0.32, 0.623±0.33, 0.711±0.40, increase in 12 months after. e-GFR 97.6±43.3, 98.9±41.0, 99.3±40.0, 96.9±40.2, 87.5±41.3, decrease in 12 months after. Conclusion: Decreasing protein concentration in formula (from 1.25 g/kg body weight to 1.00 g/kg body weight) could reduce albumin concentration in elder Japanese people.